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How do cannabinoids interact with the Endocannabinoid System?

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Our bodies spend much of their time tweaking and adjusting hormones, temperatures and pHs, all in a bid to restore their balance.

Homeostasis is the process in which the human body attempts to maintain a stable internal environment. Our bodies' natural levels are kept in check by various regulating systems, with perhaps the most important system being our endocannabinoid system (ECS).

Given the extensive power that the ECS has over the way we function, it’s no wonder that this system has become increasingly studied by researchers interested in helping it function better.

On a basic level, the endocannabinoid system is made up of two types of endocannabinoid receptors: CB1 receptors found primarily in the brain, and CB2 receptors found throughout the body in our cells and immune system. Together, these receptors continuously monitor changes in our bodies and act as a kind of checkpoint, keeping track of various levels and making adjustments where necessary.

Cannabinoids are tiny molecules that slot into these ECS receptors in the same way that keys fit into locks. The joining of these two elements allows the body to make necessary adjustments, turning the receptors ‘on’ or ‘off’ depending on what it needs in that moment.

For example, if someone is suffering from anxiety, a specific cannabinoid joining with a specific receptor can adjust the levels of cell reproduction and growth until they’re within a healthy range that addresses the problem. (Which receptors these cannabinoids interact with and the extent to which they engage the receptor determines the strength of their effect on the body.)

Our bodies naturally produce cannabinoids to help regulate the ECS. These are known as endogenous cannabinoids (i.e. endocannabinoids) and include  molecules like 2-arachidonoylglycerol (2-AG) and anandamide (AEA).

There’s also a second class of cannabinoids, known as exogenous cannabinoids, which are not produced by our bodies — but consist of a remarkably similar structure to those we make ourselves. And thanks to extensive ongoing research, scientists have discovered that it’s now possible to restore the body’s balance by consuming these exogenous cannabinoids, such as CBD and CBG.

Cellular Goods formulates its range with exogenous cannabinoids, which makes incorporating these balancing molecules into your daily routine effortless. For more information, explore our line of ingestible solutions, including oral drops, oral spray and capsules.

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